Zoology 510, Class Notes for Ridley, Chapter 10
Quantitative Genetics.
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Brief Outline
510 index page
Introductory comments.
510 index page
Overview.
CHECK LIST of important CONCEPTS and TERMS
Chapter 10, Section-by-Section Comments
10.1. "Non-Mendelian processes must be added to classical population genetics to explain the evolution of the whole genome."
- "Non-Mendelian" is used here simply as a term for concepts or patterns of organization which lie outside of the Mendelian framework.
- The most basic "non-Mendelian" question might be, simply, WHY do genes behave according to Mendelian rules? In other words, why is DNA organized in the way it is, with independently-assorting chromosomes containing genes which recombine?
- Additional questions:
What explains the total amount of DNA in a genome (which is generally much greater the amount of protein-coding sequence)?
What explains the numbers and arrangements of genes on the chromosomes?
What explains the various patterns of non-coding DNA found in the chromosomes?
10.2. "Genes are arranged in gene clusters."
10.3. "Gene clusters probably originated by gene duplication."
10.4. "The genes in a gene family often evolve in concert."
10.5. "Not all DNA codes for genes."
10.6. "Repetitive DNA other than in gene clusters may be selfish DNA.."
10.7. "Minisatellites are sequences of short repeats, found scattered through the genome."
10.8. "Scattered repeats may originate by transposition."
10.9. "Selfish DNA may explain the C-factor paradox."
10.10. "Conclusion."
510 index page
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Last updated: 28-Feb-2000 / dgk